Yoga Improves Sperm Quality, Reduces DNA Damage in Infertile Men: AIIMS Study
Yoga Boosts Sperm Quality, Cuts DNA Damage: AIIMS

A recent study conducted by researchers at the All India Institute of Medical Sciences (AIIMS) has found that yoga can significantly improve sperm quality and reduce oxidative stress and DNA damage in men experiencing infertility. The findings were published in the International Journal of Yoga ahead of the International Day of Yoga on June 21.

Study Details and Methodology

Led by Dr. Prabhakar Tiwari, Dr. Rajeev Kumar, Dr. Rima Dada, and Anjali Yadav, the study evaluated the impact of a 12-week structured yoga intervention on seminal oxidative stress, sperm quality, and DNA fragmentation in men with primary infertility. A total of 78 infertile men aged 25 to 40 years were enrolled, with 42 completing the full programme. The intervention included yoga postures, breathing exercises, meditation, and relaxation techniques practiced for one hour daily, five days a week.

Key Findings

The researchers observed significant improvements in several key fertility parameters after the intervention. There was a sharp decline in oxidative stress and oxidative DNA damage. The study reported that regular yoga practice significantly enhances sperm function and reduces oxidative stress and DNA damage in infertile men. Although a declining trend was noted in the sperm DNA Fragmentation Index (DFI), a measure of sperm DNA damage, the reduction did not reach statistical significance. Dr. Dada noted that at least six months of regular yoga practice may be required to show significant improvement in DNA quality.

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Background on Male Infertility

Male infertility affects more than 15 percent of couples worldwide, with male factors contributing to nearly half of all cases. Unexplained male factor infertility is rising and is linked to unhealthy lifestyles, obesity, smoking, alcohol consumption, stress, pollution, exposure to micronanoplastics, and delayed marriage and childbearing. Dr. Dada explained that these factors damage mitochondria, leading to oxidative stress that can harm sperm DNA, shorten telomeres, alter methylation patterns, and affect the epigenetic landscape. Sperm with damaged DNA is associated with infertility, recurrent pregnancy losses, autosomal dominant disorders, childhood cancers, and complex neuropsychiatric disorders.

Mechanisms of Yoga's Benefits

According to the researchers, yoga may exert its beneficial effects through multiple mechanisms, including reducing stress hormones, improving antioxidant defence systems, enhancing blood circulation to reproductive organs, lowering inflammation, improving mitochondrial integrity, and increasing total antioxidant capacity and telomerase levels.

Implications for Fertility Care

The study highlights the importance of integrating evidence-based lifestyle interventions into fertility care. Dr. Dada emphasized that oxidative stress is a major contributor to poor sperm quality and DNA damage, and that a structured yoga intervention can significantly reduce oxidative stress markers while improving sperm count and motility. As a safe, accessible, and cost-effective practice, yoga can serve as an important complementary strategy in the management of male infertility. The researchers concluded that yoga represents a promising non-pharmacological approach to improving reproductive health and may help reduce the burden of infertility among couples seeking conception.

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